Colloquium Schedule

Colloquium: Thursday, November 14th, 4:25 PM, Lewis Lab 316

Understanding and Controlling the Mechanical Behavior of Living Tissues Inside Developing Embryos

Karen Kasza

Columbia University
During embryonic development, an unstructured ball of cells is transformed into the diverse structures of tissues and organs in animals. During this process of morphogenesis, tissues comprising tightly packed groups of cells often dramatically deform and flow as the embryo develops and takes on its final shape. The mechanical behaviors of living tissues are crucial for generating organs with the proper shape and function, yet remain poorly understood. Our goal has been to develop experimental approaches to dissect the physical and biological mechanisms that contribute to morphogenesis. We combine novel optogenetic technologies for controlling tissue mechanics with live confocal imaging of tissues to study morphogenesis in the developing fruit fly embryo.

We will discuss examples of how active forces, adhesion between cells, and tissue anisotropy contribute to the remarkable mechanical behaviors of developing two-dimensional epithelial tissue sheets. This work provides a foundation for integrating the physics of living matter into our understanding of embryonic development and may motivate new strategies for building and shaping biological matter in the lab.

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Physics and Astronomy Colloquia are usually scheduled for Thursdays at 4:25 PM in Lewis Lab room 316. Refreshments and snacks are available in the nearby coffee room at 4:00 PM.


Physics Colloquium Schedule for Fall 2019

Click on Title below for past or upcoming Announcements (where available), and Speaker name for website.        

August 29---
September 5V. DobrosavljevicFlorida StateLandau Theory for Disorder-Driven Metal-Insulator
September 12Ivan BiaggioLehigh University The Life and Times of Excitons in an Organic "Semiconductor": Fission, Fusion, Entanglement, Transport, and Dissociation
September 19Cyrus DreyerStony BrookThe Modern Theory of Polarization with a Twist
September 26Martin ZwierleinMITThe Sound of Fermions
October 3A.L. ExarhosLafayetteCreating, Controlling, and Characterizing Quantum Emission from Hexagonal Boron Nitride
October 10Edmund WebbLehigh UniversityMultiscale Modeling of the Human Blood Protein Von Willebrand Factor
October 17Eugene MeleU. PennAnomalous Velocity and Geometry in Wave Mechanics
October 24Berndt MuellerBrookhaven NLThe Unbearable Burden of Being Light: Emergence of Ordinary Matter from Quarks and Gluons
October 31Chueng JiNCS University Proton Puzzle
Novemebr 7Gabriel KotliarRutgers UniversityTowards a Predictive Theory of Strongly Correlated Electron Materials
November 14Karen KaszaColumbia UniversityUnderstanding and controlling the mechanical behavior of living tissues inside developing embryos
November 21K. L. KnappenbergerPenn State UniversityStructural Influences on the Optical Properties Atomically Thin Metals
November 28Thanksgiving Break--
December 5Javier Perez-MorenoSkidmore CollegeApplying Sum Rules to Interpret Experimental Data from Nonlinear Molecules