Colloquium Schedule

Colloquium: Thursday, December 6th, 4:10 PM, Lewis Lab 316

Active Contraction or Expansion of Disordered Cytoskeletal Networks

François Nedelec

EMBL and EMBO Heidelberg, Germany
The cytoskeleton drives many essential processes in vivo, but for this, the system of filaments will arrange itself into different overall spatial organizations, e.g., random, branched networks, parallel bundles, antiparallel arrays, etc. A general objective of our research is to understand what makes these architectures adapted to their tasks. In this talk, I will first focus on 2D disorganized actin networks in which the filaments are oriented randomly and connected both by active molecular motors and passive crosslinkers. Systems with these properties have been reconstituted in vitro, and serve as a model of the cortical actomyosin networks that drive morphogenesis in animal tissues, or cytokinesis during cell division. Although the network components and their properties are known, the requirements for contractility are still poorly understood. I will describe a theory that predicts whether an isotropic network would contract, expand, or conserve its dimensions, depending on the properties of the filaments and the elements that connect them. This simple theory encompasses mechanisms of contractions previously proposed and predicts how the contraction rate depends for example on the ratio of motors to crosslinkers.

Click Here for full announcement

Physics and Astronomy Colloquia are usually scheduled for Thursdays at 4:10 PM in Lewis Lab room 316. Refreshments and snacks are available in the nearby coffee room at 3:45 PM.


Physics Colloquium Schedule for FALL 2018

Click on Title below for past or upcoming Announcements (where available), and Speaker name for website.        

August 30Rajarshi RoyUniv. of MarylandRandom Numbers from Light: Photons, Chaos and Entropy
September 6Markus LutyUC DavisMapping the Landscape of Quantum Field Theories
September 13Rosi ReedLehigh Univ.The STAR Event Plane Detector
September 20Lee BassettU PennThe Power of Imperfection: Embracing the Quantum Limit in Semiconductor Devices
September 27Ryan PensackBoise State Univ.Singlet Exciton Fission: Toward Molecular Packing Guidelines for Efficient Triplet Harvesting
October 4Steven GubserPrinceton Univ.Number Theory and Spacetime
October 11Robert AustinPrinceton Univ.The Physics of Cancer
October 18John ThomasN. Carolina StateScale Invariant Strongly Interacting Fermi Gases
October 25Oana JurchescuWake Forest U.Every Molecule Counts: From Single Crystals to Large Area Organic Flexible Electronics
November 1Feynman Symp.Lehigh UniversityFeynman Symposium Nov. 1st 
November 8Feynman Symp.Lehigh UniversityFeynman Symposium Nov. 8th
November 15Christopher PopeTexas A&MGravity and Black Holes
November 22No ColloquiumHappy Thanksgiving-
November 29Taviare HawkinsU. WisconsinThe Mechanics of Microtubules
December 6François NedelecEMBL HeidelbergActive Contraction or Expansion of Disordered Cytoskeletal Networks
December 11---