Colloquium Schedule

Colloquium: Thursday, March 23, 4:10 PM, Lewis Lab 316

Biopolymer Matrices: From Fundamental Questions to Applied Goals?

Laura Kaufman

Professor of Chemistry
Columbia University

My laboratory’s research on collagen I gels can be framed as a narrative of asking and answering fundamental questions to reach applied goals in biophysical studies and bioengineering applications. One such fundamental question revolves around determining key events in collagen I gelation, with a focus on the nucleation and growth entropically-driven self-assembly of collagen fibrils and subsequent fiber entanglement and network formation. An enhanced understanding of these processes would ideally lead to independent control over local and global protein content and presentation, network structural properties, and gel mechanical properties for use in physiologically relevant but well-controlled biophysical experiments, such as those interrogating signaling processes involved in cell migration in three-dimensional obstacle-strewn environments. The origin and ramifications of strain stiffening in collagen I gels have been a second area of fundamental interest, with enhanced understanding of this process potentially leading to new synthetic materials for tissue engineering as well as to biophysical experiments to interrogate the complex reciprocal mechanical interactions between cells and their local environment. I will highlight the progress and challenges in addressing these fundamental questions surrounding collagen gelation and strain stiffening and the distinct set of challenges that surrounds using the answers to these questions to achieve practical goals. Despite such challenges, I will show how even these non-ideal in vitro biopolymer gels provide opportunities for significant findings in the biophysics of cancer invasion.
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Physics and Astronomy Colloquia are usually scheduled for Thursdays at 4:10 PM in Lewis Lab room 316. Refreshments and snacks are available in the nearby coffee room at 3:45 PM.


Physics Colloquium Schedule for SPRING 2017

Click on Title below for past or upcoming Announcements (where available), and Speaker name for website.        

January 26Daniel McCarronYale UniversityUltracold Polar Molecules: Production Methods and Scientific Applications
February 2Tariq RafiqLehigh UniversityRole of Plasma Science in Making a Sun on Earth
February 9Mehul MalikInstit for Quantum Optics and Quantum Info, ViennaHigh-Dimensional Quantum Photonics: Pushing the limits of Quantum Information Science
February 16Mayukh LahiriInstit for Quantum Optics and Quantum Info, ViennaImaging and Correlation Measurements with Undetected Photons
February 23Ariel SommerMITQuantum Simulation with Cold Atoms and Trapped Photons
March 2MJ PueschelUniv. of Wisconsin-MadisonTurbulence in Magnetized Plasmas: from Fusion Reactors to Astrophysics
March 7Jane PrattUniv of Exeter, UKMagnetic Reconnection in Fusion Plasmas
March 16Spring Break--
March 23Laura KaufmanColumbia Univ.
March 30Meenaskshi DuttRutgers Univ.
April 6Bradley PetersonOhio State Univ.Exploring the Inner Structure of Active Galactic Nuclei by Reverberation
April 13Mark Trodden Univ. of Penn.
April 20Giti KhodaparastVirginia Tech.Magneto-Optical and Ultrafast Optical Phenomena in Multi-functional Materials
April 27Ahijit MajumderWayne State Univ.Resolving the Quark Gluon Plasma with Higher Precision
May 4Marlan  ScullyTexas A&MEntropy: Classical and Quantum
May 11---
May 18---